• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to secondary sidebar
  • Skip to footer
  • Home
  • Subscribe
  • Your Membership
    • Edit Your Profile
  • Services
    • Advertising
    • Case studies
    • Design
    • Email marketing
    • Lead generation
    • Magazine
    • Press releases
    • Publishing
    • Sponsored posts
    • Webcasting
    • Webinars
    • White papers
    • Writing
  • Shop
    • My Account
    • Cart
  • About
    • Contact
    • Privacy
    • Terms of use
  • Events

Robotics & Automation News

Market trends and business perspectives

  • News
  • Features
  • Sections A-Z
    • Agriculture
    • Aircraft
    • Artificial Intelligence
    • Automation
    • Autonomous vehicles
    • Business
    • Computing
    • Construction
    • Design
    • Drones
    • Economy
    • Energy
    • Engineering
    • Environment
    • Health
    • Humanoids
    • Industrial robots
    • Industry
    • Infrastructure
    • Investments
    • Logistics
    • Manufacturing
    • Marine
    • Material handling
    • Materials
    • Mining
    • Promoted
    • Research
    • Robotics
    • Science
    • Sensors
    • Service robots
    • Software
    • Space
    • Technology
    • Transportation
    • Warehouse robots
    • Wearables
  • Video
  • Webinars
  • White papers
  • Press releases
  • Featured companies
    • AMD Xilinx
    • BlueBotics
    • Elite Robot
    • RGo Robotics
    • SICK Sensor Intelligence
    • Vicor Power
organelles

Breakthrough by Exeter cell biologists

February 2, 2017 by Sophiya

organelles

Scientists have made a breakthrough in understanding how different compartments (or organelles) of human cells interact.

Organelles are the functional units of a cell. Like organs in a body, they perform specialised functions. To allow survival of the cell, organelles have to interact and cooperate. How this is mediated and regulated in the cell is an important and challenging question in cell biology.

Researchers at the University of Exeter have now discovered how two cell organelles – called peroxisomes and the endoplasmic reticulum (ER) – associate with each other at the molecular level and work together.

This cooperation is crucial for the production of specific lipids, which are essential for the function of nerve cells and can protect cells from oxidative damage.

Loss of peroxisome function leads to a range of severe or fatal disorders associated with developmental and neurological defects.

“Close contacts between peroxisomes and the ER were observed more than 50 years ago in ultrastructural studies, but the molecular mechanism remained a mystery,” said lead author Dr Michael Schrader, of the University of Exeter.

“This is the first molecular tether identified in humans, which mediates the contact between these two important cell compartments.”

The study showed that a protein at the peroxisomes called ACBD5 directly interacts with a protein at the ER, called VAPB. This interaction links both organelles together and allows transfer of lipids between them.

When the interaction between VAPB and ACBD5 is lost, the ER and peroxisomes can no longer interact and this lipid transfer appears to be prevented.

The researchers are working with experts from the Academic Medical Center in Amsterdam, where a patient with an ACBD5 deficiency has been identified and linked to a peroxisomal defect.

This patient has severe damage to the brain and retinas, affecting eyesight, and Dr Schrader said Exeter’s research and similar studies were essential if such conditions are to be diagnosed and ultimately treated.

“If we understand organelle interaction better we might also be able to use this knowledge to protect cells from certain stress conditions which are linked to age-related conditions like neurodegeneration, blindness and diabetes,” he said.

People with severe peroxisomal disorders, also known as Zellweger Spectrum Disorders, often die as children or young adults, and a new charity called Zellweger UK exists to raise awareness and to support families and sufferers.

From EurekAlert!.

Print Friendly, PDF & Email

Share this:

  • Print
  • Facebook
  • LinkedIn
  • Reddit
  • Twitter
  • Tumblr
  • Pinterest
  • Skype
  • WhatsApp
  • Telegram
  • Pocket

You might also like…

Filed Under: Sections A-Z Tagged With: cell, disorders, exeter, organelles

Join the Robotics & Automation News community

Primary Sidebar

Latest articles

  • Hesai Technology to provide lidar for planned Cratus warehouse robots
  • Associated Food Stores selects Symbotic to implement warehouse automation system
  • Figure raises $70 million Series A to support commercialization of Figure 01 humanoid robot
  • 3M highlights major global trends in materials science and charts its own way ahead
  • Apex Motion Control launches new collaborative robot
  • Siemens unveils its first virtual PLC and new automation products
  • Yaskawa takes center stage at Africa Automation Technology Fair
  • Bota Systems and Kinova partner for easy installation of force torque sensors
  • Universal Robots executive receives prestigious robotics award for contribution to robot safety
  • What are the Differences between Rapid Tooling and Conventional Tooling?

Most Read

  • Snapchat Plus Planet Order 2023 Explained
    Snapchat Plus Planet Order 2023 Explained
  • Why is Money Important in Our Lives?
    Why is Money Important in Our Lives?
  • Top 20 electric vehicle charging station companies
    Top 20 electric vehicle charging station companies
  • Difference Between Three-Phase and Single-Phase Power
    Difference Between Three-Phase and Single-Phase Power
  • How to Track a Phone Number on Google Maps
    How to Track a Phone Number on Google Maps
  • Why is My Car Key Stuck in the Ignition?
    Why is My Car Key Stuck in the Ignition?
  • Scientists have found more water in space than they ever knew possible
    Scientists have found more water in space than they ever knew possible
  • Deep Robotics unveils new four-legged robot
    Deep Robotics unveils new four-legged robot
  • Top 20 programmable logic controller manufacturers
    Top 20 programmable logic controller manufacturers
  • The Future of Personal Computers: What to Expect in the Next Decade
    The Future of Personal Computers: What to Expect in the Next Decade

Overused words

ai applications automated automation automotive autonomous business companies company control customers data design development digital electric global industrial industry logistics machine manufacturing market mobile operations platform process production robot robotic robotics robots safety software solution solutions system systems technologies technology time vehicle vehicles warehouse work

Secondary Sidebar

Latest news

  • Hesai Technology to provide lidar for planned Cratus warehouse robots
  • Associated Food Stores selects Symbotic to implement warehouse automation system
  • Figure raises $70 million Series A to support commercialization of Figure 01 humanoid robot
  • 3M highlights major global trends in materials science and charts its own way ahead
  • Apex Motion Control launches new collaborative robot
  • Siemens unveils its first virtual PLC and new automation products
  • Yaskawa takes center stage at Africa Automation Technology Fair
  • Bota Systems and Kinova partner for easy installation of force torque sensors
  • Universal Robots executive receives prestigious robotics award for contribution to robot safety
  • What are the Differences between Rapid Tooling and Conventional Tooling?

Footer

We are…

Robotics and Automation News was established in May, 2015, and is now one of the most widely-read websites in its category.

Please consider supporting us by becoming a paying subscriber, or through advertising and sponsorships, or by purchasing products and services through our shop – or a combination of all of the above.

Thank you.

Independent

Archivists

February 2017
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728  
« Jan   Mar »

Complex

Old-skool

This website and its associated magazine, and weekly newsletter, are all produced by a small team of experienced journalists and media professionals.

If you have any suggestions or comments, feel free to contact us at any of the email addresses on our contact page.

We’d be happy to hear from you, and will always reply as soon as possible.

Future-facing

Free, fair and legal

We support the principles of net neutrality and equal opportunities.

Member of The Internet Defense League

Copyright © 2023 · News Pro on Genesis Framework · WordPress · Log in

We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept”, you consent to the use of ALL the cookies.
Do not sell my personal information.
Cookie SettingsAccept
Manage consent

Privacy Overview

This website uses cookies to improve your experience while you navigate through the website. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may affect your browsing experience.
Necessary
Always Enabled
Necessary cookies are absolutely essential for the website to function properly. These cookies ensure basic functionalities and security features of the website, anonymously.
CookieDurationDescription
cookielawinfo-checkbox-analytics11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics".
cookielawinfo-checkbox-functional11 monthsThe cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional".
cookielawinfo-checkbox-necessary11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-others11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other.
cookielawinfo-checkbox-performance11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance".
viewed_cookie_policy11 monthsThe cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
Functional
Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features.
Performance
Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors.
Analytics
Analytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc.
Advertisement
Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. These cookies track visitors across websites and collect information to provide customized ads.
Others
Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet.
SAVE & ACCEPT